N. Louise Glass
N. Louise Glass
Biofuels, Fungi
Professor, Chair, Plant & Microbial Biology
341A Koshland Hall
Berkeley, California 94720
Phone 510.643.2399
Lab Phone 510.643.2546
Fax 510.642.4995

CV

Ph.D.  University of California-Davis, 1986

Cell specialization, cell communication and nonself recognition are crucial mechanisms in filamentous fungi. Neurospora crassa's experimental tractability make it a superb system to address microbial communication questions. We study communication and self-signaling mechanisms mediating hyphal fusion, and nonself recognition mechanisms resulting in programmed cell death. We use molecular biology, genetics, cell biology, genomics and bioinformatics to investigate the molecular and cellular basis of nonself recognition during the filamentous fungi lifecycle.

Research

Molecular Genetics of Filamentous Fungi

Cell specialization, cell communication and nonself recognition are crucial mechanisms in microbial organisms such as filamentous fungi. In filamentous fungi, growth occurs by hyphal tip extension, branching and repeated fusion of hyphae, ultimately forming an exquisitely connected network, from which the individual colony grows and reproduces. My research interests are focused on understanding communication and signaling mechanisms that mediate the hyphal fusion process and nonself recognition mechanisms that occur before and after hyphal fusion. The experimental tractability and availability of a large number of mutants in the filamentous fungus, Neurospora crassa, makes it a superb system to delineate both fungal-specific and general mechanisms of cell communication and nonself recognition. We use a combination of molecular biology, genetics, cell biology, genomics and bioinformatics to investigate the molecular and cellular basis of nonself recognition during both sexual and asexual phases of growth in filamentous fungi.


Nonself Recognition and Programmed Cell Deathincompatible colony

Self/nonself discrimination is a ubiquitous and essential function of both multicellular and microbial species, and is an aspect of biology that has long fascinated scientists. Nonself recognition in filamentous fungi is mediated by differences at het (for heterokaryon incompatibility) loci. Hyphal fusion between two individuals that have genetic differences at het loci triggers programmed cell death (PCD)of the fusion cell. Nonself recognition and PCD functions to prevent transfer of mycoviruses and senescence plasmids between fungal individuals within a population. Our current research objectives include elucidating the molecular mechanism of nonself recognition, understanding how nonself recognition triggers fungal PCD and investigations into the evolution of nonself recognition systems in fungi.

Germling and hyphal fusion

hyphal fusion eventsThe ability to form a hyphal network is a hallmark of filamentous fungi. In filamentous ascomycete species such as Neurospora crassa, an individual hypha (a multinucleate, multicellular filament with incomplete crosswalls, or septa) grows by hyphal tip extension and branching. Behind the growing colony margin, fusions between hyphae are continuously formed (a process called anastomosis), yielding a network of interconnected hyphae, or mycelium, that makes up the fungal individual. Although the capacity to form a hyphal network is ubiquitous in filamentous fungi, little is known about the mechanism or function of an interconnected hyphal network. We have characterized a number of hyphal and germling fusion mutants in N. crassa, including strains with lesions in genes encoding MAP kinase signal transduction components and a number of transcription factors. Our current research objectives include determining the molecular mechanism of self-signling and the nature of the signaling molecules, the relationship of the signal transduction pathway to the fungal cytoskeleton and identifying target genes of transcription factors which are required for the germling and fusion process.

Plant cell wall deconstruction by Neurospora crassa

Field of Miscanthus.In nature, filamentous fungi are the primary degraders of plant biomass. Plant biomass is a potential source for the production of biofuels. Neurospora crassa is an efficient degrader of plant cellulose and hemicellulose and is found in nature primarily on grasses. In a project funded by the Energy Biosciences Institute, we are using the genomic and genetic tools available with N. crassa to decipher transcriptional, secretory and enzymatic regulatory mechanisms associated with plant cell wall deconstruction. These efforts have the potential to provide tools and components that can be used to optimize plant biomass utilization for the production of biofuels.

Recent Publications

To download publications please visit glasslab.berkeley.edu/publications

2014

  • Benz PJ, Chau BH, Zheng D, Bauer S, Glass LN, Somerville CR.  2014.  A comparative systems analysis of polysaccharide-elicited responses in Neurospora crassa reveals carbon source-specific cellular adaptations. Molecular microbiology. 91(2):275-99.PubMed

2013

  • Coradetti ST, Xiong Y, Glass NL.  2013.  Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa. MicrobiologyOpen. 2(4):595-609.PubMed
  • Znameroski EA, Li X, Tsai JC, Galazka JM, Glass LN, Cate JHD.  2013.  Evidence for transceptor function of cellodextrin transporters in Neurospora crassa. The Journal of biological chemistry. PubMed
  • Palma-Guerrero J, Hall CR, Kowbel D, Welch J, Taylor JW, Brem RB, Glass NL.  2013.  Genome wide association identifies novel Loci involved in fungal communication. PLoS genetics. 9(8):e1003669.PubMed
  • Leeder AC, Jonkers W, Li J, Glass NL.  2013. Early Colony Establishment in Neurospora crassa Requires a MAP Kinase Regulatory Network. Genetics. PubMed
  • Roper M, Simonin A, Hickey PC, Leeder A, Glass NL.  2013.  Nuclear dynamics in a fungal chimera. Proceedings of the National Academy of Sciences of the United States of America. 110(32):12875-80.PubMed
  • Roche CM, Blanch HW, Clark DS, Glass NL.  2013.  Physiological Role of Acyl Coenzyme A Synthetase Homologs in Lipid Metabolism in Neurospora crassa. Eukaryotic cell. 12(9):1244-57.PubMed
  • Glass NL, Schmoll M, Cate JHD, Coradetti S.  2013.  Plant cell wall deconstruction by ascomycete fungi. Annual review of microbiology. 67:477-98.PubMed
  • Znameroski EA, Glass NL.  2013.  Using a model filamentous fungus to unravel mechanisms of lignocellulose deconstruction. Biotechnology for biofuels. 6(1):6.PubMed

2012

  • Coradetti ST, Craig JP, Xiong Y, Shock T, Tian C, Glass NL.  2012.  Conserved and essential transcription factors for cellulase gene expression in ascomycete fungi. Proceedings of the National Academy of Sciences of the United States of America. 109(19):7397-402.PubMed
  • Richard F, Glass NL, Pringle A.  2012.  Cooperation among germinating spores facilitates the growth of the fungus, Neurospora crassa. Biology letters. 8(3):419-22.PubMed
  • Sun J, Tian C, Diamond S, Glass NL.  2012.  Deciphering transcriptional regulatory mechanisms associated with hemicellulose degradation in Neurospora crassa. Eukaryotic cell. 11(4):482-93.PubMed
  • Hutchison EA, Bueche JA, Glass NL.  2012.  Diversification of a protein kinase cascade: IME-2 is involved in nonself recognition and programmed cell death in Neurospora crassa. Genetics. 192(2):467-82.PubMed
  • Znameroski EA, Coradetti ST, Roche CM, Tsai JC, Iavarone AT, Cate JHD, Glass NL.  2012.  Induction of lignocellulose-degrading enzymes in Neurospora crassa by cellodextrins. Proceedings of the National Academy of Sciences of the United States of America. 109(16):6012-7.PubMed
  • Simonin A, Palma-Guerrero J, Fricker M, Glass NL.  2012.  Physiological significance of network organization in fungi. Eukaryotic cell. 11(11):1345-52.PubMed
  • Schmoll M, Tian C, Sun J, Tisch D, Glass NL.  2012.  Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa. BMC genomics. 13:127.PubMed

2011

  • Gilbert LB, Kasuga T, Glass NL, Taylor JW.  2011.  Array CGH phylogeny: how accurate are comparative genomic hybridization-based trees? BMC Genomics. 12:487.PubMed
  • Ha S-J, Galazka JM, Kim S R, Choi J-H, Yang X, Seo J-H, Glass NL, Cate JHD, Jin Y-S.  2011.  Engineered Saccharomyces cerevisiae capable of simultaneous cellobiose and xylose fermentation. Proceedings of the National Academy of Sciences of the United States of America. 108(2):504-9.PubMed
  • Tian C, Li J, Glass NL.  2011.  Exploring the bZIP transcription factor regulatory network in Neurospora crassa. Microbiology (Reading, England). 157(Pt 3):747-59.PubMed
  • Sun J, Phillips CM, Anderson CT, Beeson WT, Marletta MA, Glass NL.  2011.  Expression and characterization of the Neurospora crassa endoglucanase GH5-1. Protein expression and purification. 75(2):147-54.PubMed
  • Sun J, Glass NL.  2011.  Identification of the CRE-1 cellulolytic regulon in Neurospora crassa. PloS one. 6(9):e25654.PubMed
  • Fernandes AS, Gonçalves PA, Castro A, Lopes TA, Gardner R, Glass NL, Videira A.  2011.  Modulation of fungal sensitivity to staurosporine by targeting proteins identified by transcriptional profiling. Fungal genetics and biology : FG & B. 48(12):1130-8.PubMed
  • Roper M, Ellison C, Taylor JW, Glass NL.  2011.  Nuclear and genome dynamics in multinucleate ascomycete fungi. Current biology : CB. 21(18):R786-93.
  • Ellison CE, Hall C, Kowbel D, Welch J, Brem RB, Glass NL, Taylor JW.  2011. Population genomics and local adaptation in wild isolates of a model microbial eukaryote. Proceedings of the National Academy of Sciences of the United States of America. 108(7):2831-6.
  • Leeder AC, Palma-Guerrero J, Glass NL.  2011.  The social network: deciphering fungal language. Nature reviews. Microbiology. 9(6):440-51.PubMed

2010

  • Galazka JM, Tian C, Beeson WT, Martinez B, Glass NL, Cate JHD.  2010.  Cellodextrin transport in yeast for improved biofuel production. Science (New York, N.Y.). 330(6000):84-6.PubMed
  • Hall C, Welch J, Kowbel DJ, Glass NL.  2010.  Evolution and diversity of a fungal self/nonself recognition locus. PloS one. 5(11):e14055.PubMed
  • Simonin AR, Rasmussen CG, Yang M, Glass NL.  2010.  Genes encoding a striatin-like protein (ham-3) and a forkhead associated protein (ham-4) are required for hyphal fusion in Neurospora crassa. Fungal genetics and biology : FG & B. 47(10):855-68.PubMed
  • Hutchison EA, Glass NL.  2010.  Meiotic regulators Ndt80 and ime2 have different roles in Saccharomyces and Neurospora. Genetics. 185(4):1271-82.PubMed
  • Li S, Du J, Sun J, Galazka JM, Glass NL, Cate JHD, Yang X, Zhao H.  2010.  Overcoming glucose repression in mixed sugar fermentation by co-expressing a cellobiose transporter and a β-glucosidase in Saccharomyces cerevisiae. Molecular bioSystems. 6(11):2129-32.PubMed
  • Castro A, Lemos C, Falcão A, Fernandes AS, Glass NL, Videira A.  2010.  Rotenone enhances the antifungal properties of staurosporine. Eukaryotic cell. 9(6):906-14.PubMed
  • Greenwald CJ, Kasuga T, Glass NL, Shaw BD, Ebbole DJ, Wilkinson HH.  2010.  Temporal and spatial regulation of gene expression during asexual development of Neurospora crassa. Genetics. 186(4):1217-30.PubMed

2009

  • Fleissner A, Leeder AC, Roca GM, Read ND, Glass NL.  2009.  Oscillatory recruitment of signaling proteins to cell tips promotes coordinated behavior during cell fusion. Proceedings of the National Academy of Sciences of the United States of America. 106(46):19387-92.PubMed
  • Kasuga T, Mannhaupt G, Glass NL.  2009.  Relationship between phylogenetic distribution and genomic features in Neurospora crassa. PloS one. 4(4):e5286.PubMed
  • Fleissner A, Diamond S, Glass NL.  2009.  The Saccharomyces cerevisiae PRM1 homolog in Neurospora crassa is involved in vegetative and sexual cell fusion events but also has postfertilization functions. Genetics. 181(2):497-510.PubMed
  • Tian C, Beeson WT, Iavarone AT, Sun J, Marletta MA, Cate JHD, Glass NL.  2009.  Systems analysis of plant cell wall degradation by the model filamentous fungus Neurospora crassa. Proceedings of the National Academy of Sciences of the United States of America. 106(52):22157-62.PubMed
  • Videira A, Kasuga T, Tian C, Lemos C, Castro A, Glass NL.  2009.  Transcriptional analysis of the response of Neurospora crassa to phytosphingosine reveals links to mitochondrial function. Microbiology (Reading, England). 155(Pt 9):3134-41.PubMed
  • Hutchison E, Brown S, Tian C, Glass NL.  2009.  Transcriptional profiling and functional analysis of heterokaryon incompatibility in Neurospora crassa reveals that reactive oxygen species, but not metacaspases, are associated with programmed cell death. Microbiology (Reading, England). 155(Pt 12):3957-70.PubMed

2008

  • Fleissner A, Simonin AR, Glass NL.  2008.  Cell fusion in the filamentous fungus, Neurospora crassa. Methods in molecular biology (Clifton, N.J.). 475:21-38.PubMed
  • Kasuga T, Glass NL.  2008.  Dissecting colony development of Neurospora crassa using mRNA profiling and comparative genomics approaches. Eukaryotic cell. 7(9):1549-64.PubMed
  • Castro A, Lemos C, Falcão A, Glass NL, Videira A.  2008.  Increased resistance of complex I mutants to phytosphingosine-induced programmed cell death. The Journal of biological chemistry. 283(28):19314-21.PubMed
  • Rasmussen CG, Morgenstein RM, Peck S, Glass NL.  2008.  Lack of the GTPase RHO-4 in Neurospora crassa causes a reduction in numbers and aberrant stabilization of microtubules at hyphal tips. Fungal genetics and biology : FG & B. 45(6):1027-39.PubMed
  • Wichmann G, Sun J, Dementhon K, Glass NL, Lindow SE.  2008.  A novel gene, phcA from Pseudomonas syringae induces programmed cell death in the filamentous fungus Neurospora crassa. Molecular microbiology. 68(3):672-89.PubMed

2007

  • Dunlap JC, Borkovich KA, Henn MR, Turner GE, Sachs MS, Glass NL, McCluskey K, Plamann M, Galagan JE, Birren BW et al..  2007.  Enabling a community to dissect an organism: overview of the Neurospora functional genomics project. Advances in genetics. 57:49-96.PubMed
  • Rasmussen CG, Glass NL.  2007.  Localization of RHO-4 indicates differential regulation of conidial versus vegetative septation in the filamentous fungus Neurospora crassa. Eukaryotic cell. 6(7):1097-107.PubMed
  • Fleissner A, Glass NL.  2007.  SO, a protein involved in hyphal fusion in Neurospora crassa, localizes to septal plugs. Eukaryotic cell. 6(1):84-94.PubMed
  • Tian C, Kasuga T, Sachs MS, Glass NL.  2007.  Transcriptional profiling of cross pathway control in Neurospora crassa and comparative analysis of the Gcn4 and CPC1 regulons. Eukaryotic cell. 6(6):1018-29.PubMed

2006

  • Kaneko I, Dementhon K, Xiang Q, Glass NL.  2006.  Nonallelic interactions between het-c and a polymorphic locus, pin-c, are essential for nonself recognition and programmed cell death in Neurospora crassa. Genetics. 172(3):1545-55.PubMed
  • Glass NL, Dementhon K.  2006.  Non-self recognition and programmed cell death in filamentous fungi. Current opinion in microbiology. 9(6):553-8.PubMed
  • Dementhon K, Iyer G, Glass NL.  2006.  VIB-1 is required for expression of genes necessary for programmed cell death in Neurospora crassa. Eukaryotic cell. 5(12):2161-73.PubMed

2005

  • Kasuga T, Townsend JP, Tian C, Gilbert LB, Mannhaupt G, Taylor JW, Glass NL.  2005.  Long-oligomer microarray profiling in Neurospora crassa reveals the transcriptional program underlying biochemical and physiological events of conidial germination. Nucleic acids research. 33(20):6469-85.PubMed
  • Rasmussen CG, Glass NL.  2005.  A Rho-type GTPase, rho-4, is required for septation in Neurospora crassa. Eukaryotic cell. 4(11):1913-25.PubMed
  • Fleissner A, Sarkar S, Jacobson DJ, Roca GM, Read ND, Glass NL.  2005.  The so locus is required for vegetative cell fusion and postfertilization events in Neurospora crassa. Eukaryotic cell. 4(5):920-30.PubMed

2004

  • Xiang Q, Glass NL.  2004.  Chromosome rearrangements in isolates that escape from het-c heterokaryon incompatibility in Neurospora crassa. Current genetics. 44(6):329-38.PubMed
  • Xiang Q, Glass NL.  2004.  The control of mating type heterokaryon incompatibility by vib-1, a locus involved in het-c heterokaryon incompatibility in Neurospora crassa. Fungal genetics and biology : FG & B. 41(12):1063-76.PubMed
  • Glass NL, Rasmussen C, Roca GM, Read ND.  2004.  Hyphal homing, fusion and mycelial interconnectedness. Trends in microbiology. 12(3):135-41.PubMed
  • Jacobson DJ, Powell AJ, Dettman JR, Saenz GS, Barton MM, Hiltz MD, Dvorachek WH, Glass NL, Taylor JW, Natvig DO.  2004.  Neurospora in temperate forests of western North America. Mycologia. 96(1):66-74.PubMed
  • Pandey A, Roca GM, Read ND, Glass NL.  2004.  Role of a mitogen-activated protein kinase pathway during conidial germination and hyphal fusion in Neurospora crassa. Eukaryotic cell. 3(2):348-58.PubMed

2003

  • Glass NL, Kaneko I.  2003.  Fatal attraction: nonself recognition and heterokaryon incompatibility in filamentous fungi. Eukaryotic cell. 2(1):1-8.PubMed
  • Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read ND, Jaffe D, FitzHugh W, Ma L-J, Smirnov S, Purcell S et al..  2003.  The genome sequence of the filamentous fungus Neurospora crassa. Nature. 422(6934):859-68.PubMed
  • Kroken S, Glass NL, Taylor JW, Yoder OC, Turgeon GB.  2003.  Phylogenomic analysis of type I polyketide synthase genes in pathogenic and saprobic ascomycetes. Proceedings of the National Academy of Sciences of the United States of America. 100(26):15670-5.PubMed

2002

  • Xiang Q, Rasmussen C, Glass NL.  2002.  The ham-2 locus, encoding a putative transmembrane protein, is required for hyphal fusion in Neurospora crassa. Genetics. 160(1):169-80.PubMed
  • Xiang Q, Glass NL.  2002.  Identification of vib-1, a locus involved in vegetative incompatibility mediated by het-c in Neurospora crassa. Genetics. 162(1):89-101.PubMed
  • Muirhead CA, Glass NL, Slatkin M.  2002.  Multilocus self-recognition systems in fungi as a cause of trans-species polymorphism. Genetics. 161(2):633-41.PubMed
  • Sarkar S, Iyer G, Wu J, Glass NL.  2002.  Nonself recognition is mediated by HET-C heterocomplex formation during vegetative incompatibility. The EMBO journal. 21(18):4841-50.PubMed

2001

  • Wu J, Glass NL.  2001.  Identification of specificity determinants and generation of alleles with novel specificity at the het-c heterokaryon incompatibility locus of Neurospora crassa. Molecular and cellular biology. 21(4):1045-57.PubMed

2000

  • Shiu PK, Glass NL.  2000.  Cell and nuclear recognition mechanisms mediated by mating type in filamentous ascomycetes. Current opinion in microbiology. 3(2):183-8.PubMed
  • Glass NL, Jacobson DJ, Shiu PK.  2000.  The genetics of hyphal fusion and vegetative incompatibility in filamentous ascomycete fungi. Annual review of genetics. 34:165-186.PubMed
  • Smith ML, Hubbard SP, Jacobson DJ, Micali OC, Glass NL.  2000.  An osmotic-remedial, temperature-sensitive mutation in the allosteric activity site of ribonucleotide reductase in Neurospora crassa. Molecular & general genetics : MGG. 262(6):1022-35.PubMed
  • Smith ML, Micali OC, Hubbard SP, Mir-Rashed N, Jacobson DJ, Glass NL.  2000.  Vegetative incompatibility in the het-6 region of Neurospora crassa is mediated by two linked genes. Genetics. 155(3):1095-104.PubMed

1999

  • Shiu PK, Glass NL.  1999.  Molecular characterization of tol, a mediator of mating-type-associated vegetative incompatibility in Neurospora crassa. Genetics. 151(2):545-55.PubMed

1998

  • Ferreira AV, An Z, Metzenberg RL, Glass NL.  1998.  Characterization of mat A-2, mat A-3 and deltamatA mating-type mutants of Neurospora crassa. Genetics. 148(3):1069-79.PubMed
  • Wu J, Saupe SJ, Glass NL.  1998.  Evidence for balancing selection operating at the het-c heterokaryon incompatibility locus in a group of filamentous fungi. Proceedings of the National Academy of Sciences of the United States of America. 95(21):12398-403.PubMed
  • Kuldau GA, Raju NB, Glass NL.  1998.  Repeat-induced point mutations in Pad-1, a putative RNA splicing factor from Neurospora crassa, confer dominant lethal effects on ascus development. Fungal genetics and biology : FG & B. 23(2):169-80.PubMed

1997

  • Saupe SJ, Glass NL.  1997.  Allelic specificity at the het-c heterokaryon incompatibility locus of Neurospora crassa is determined by a highly variable domain. Genetics. 146(4):1299-309.PubMed

1996

  • Smith ML, Yang CJ, Metzenberg RL, Glass NL.  1996.  Escape from het-6 incompatibility in Neurospora crassa partial diploids involves preferential deletion within the ectopic segment. Genetics. 144(2):523-31.PubMed
  • Smith ML, Glass NL.  1996.  Mapping translocation breakpoints by orthogonal field agarose-gel electrophoresis. Current genetics. 29(3):301-5.PubMed
  • Saupe S, Stenberg L, Shiu KT, Griffiths AJ, Glass NL.  1996.  The molecular nature of mutations in the mt A-1 gene of the Neurospora crassa A idiomorph and their relation to mating-type function. Molecular & general genetics : MGG. 250(1):115-22.PubMed
  • Saupe SJ, Kuldau GA, Smith ML, Glass NL.  1996.  The product of the het-C heterokaryon incompatibility gene of Neurospora crassa has characteristics of a glycine-rich cell wall protein. Genetics. 143(4):1589-600.PubMed
  • Ferreira AV, Saupe S, Glass NL.  1996.  Transcriptional analysis of the mtA idiomorph of Neurospora crassa identifies two genes in addition to mtA-1. Molecular & general genetics : MGG. 250(6):767-74.PubMed

1995

  • Glass NL, Donaldson GC.  1995.  Development of primer sets designed for use with the PCR to amplify conserved genes from filamentous ascomycetes. Applied and environmental microbiology. 61(4):1323-30.PubMed
  • Donaldson GC, Ball LA, Axelrood PE, Glass NL.  1995.  Primer sets developed to amplify conserved genes from filamentous ascomycetes are useful in differentiating fusarium species associated with conifers. Applied and environmental microbiology. 61(4):1331-40.PubMed

1994

  • Grotelueschen J, Peleg Y, Glass NL, Metzenberg RL.  1994.  Cloning and characterization of the pho-2+ gene encoding a repressible alkaline phosphatase in Neurospora crassa. Gene. 144(1):147-8.PubMed
  • Vellani TS, Griffiths AJ, Glass NL.  1994.  New mutations that suppress mating-type vegetative incompatibility in Neurospora crassa. Genome / National Research Council Canada = Génome / Conseil national de recherches Canada. 37(2):249-55.PubMed
  • Glass NL, Smith ML.  1994.  Structure and function of a mating-type gene from the homothallic species Neurospora africana. Molecular & general genetics : MGG. 244(4):401-9.PubMed

1993

  • Arnaise S, Zickler D, Glass NL.  1993.  Heterologous expression of mating-type genes in filamentous fungi. Proceedings of the National Academy of Sciences of the United States of America. 90(14):6616-20.PubMed

1992

  • Glass NL, Lee L.  1992.  Isolation of Neurospora crassa A mating type mutants by repeat induced point (RIP) mutation. Genetics. 132(1):125-33.PubMed
  • Glass NL, Kuldau GA.  1992.  Mating type and vegetative incompatibility in filamentous ascomycetes. Annual review of phytopathology. 30:201-24.PubMed

1990

  • Metzenberg RL, Glass NL.  1990.  Mating type and mating strategies in Neurospora. BioEssays : news and reviews in molecular, cellular and developmental biology. 12(2):53-9.PubMed
  • Glass NL, Grotelueschen J, Metzenberg RL.  1990.  Neurospora crassa A mating-type region. Proceedings of the National Academy of Sciences of the United States of America. 87(13):4912-6.PubMed
  • Klem SA, Pollack MM, Glass NL, Spohn WA, Kanter RK, Zucker AR, Ruttimann UE.  1990.  Resource use, efficiency, and outcome prediction in pediatric intensive care of trauma patients. The Journal of trauma. 30(1):32-6.PubMed

 

Honors and Awards

  • Miller Professorship - 2012
  • Fellow - American Academy of Microbiology, American Society for Microbiology - 2010
  • Fellow - American Association for the Advancement of Science - 2005