The Freeling lab (circa 1973) combines genomes and ENCODE-like datasets in sequenced plants, especially including “mesopolyploids” like maize and the Brassicas, to better understand evolutionary trends and gene regulation. See Freeling’s Google Citations page and the Freeling Lab website. Longtime lab PI Damon Lisch is now a professor at Purdue University. Lab Ph.D. researchers: Margaret Woodhouse and Diane Burgess.
The Freeling lab is presently funded by NSF and NIFA, and will be funded at some level into 2017. We are closed to graduate and postdoctoral student talent unless co-sponsored by another, younger PI.
Freeling teaches as part of the Plant Biology graduate student core curriculum.
Specific research includes 1) conserved noncoding sequences, 2) genome dominance, its relationship to RNA-dependent DNA methylation and to possible functions for bulk junk DNA. 3) the regulation of gene product quantity, and 4) using fractionation mutagenesis to better understand the nature of the plant gene. Funded collaboration with John Fowler and Mike Scanlon.